An overview of pharmaceutical cocrystals as intellectual property.
نویسنده
چکیده
This review article focuses on the interaction among certain scientific, legal, and regulatory aspects of pharmaceutical crystal forms. The article offers an analysis of pharmaceutical cocrystals as patentable inventions by drawing upon recent scientific developments in the field. Several potential commercial advantages of pharmaceutical cocrystals are highlighted, and a number of recent court decisions involving salient issues are summarized. The article provides an outlook on how the developing field of cocrystallization may impact the pharmaceutical intellectual property landscape.
منابع مشابه
High-throughput 96-well cocrystal screening workflow for active pharmaceutical ingredients
Increasingly, poorly soluble drug candidates are entering development, which has made identifying and selecting stable solid forms of an active pharmaceutical ingredient (API) with enhanced in vivo absorption more difficult. While pharmaceutical salts are the most common choice for solid forms, cocrystals are also known to improve “druggability” characteristics such as solubility, dissolution, ...
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This review article will highlight and discuss the advances made over the last 10 years pertaining to physical and chemical property improvements through pharmaceutical cocrystals and, hopefully, draw closer the fields of crystal engineering and pharmaceutical sciences.
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عنوان ژورنال:
- Molecular pharmaceutics
دوره 4 3 شماره
صفحات -
تاریخ انتشار 2007